Vision-Language Models and Large Language Models in Medical Applications

Report on Current Developments in Vision-Language Models and Large Language Models in Medical Applications

General Direction of the Field

The recent advancements in Vision-Language Models (VLMs) and Large Language Models (LLMs) have significantly influenced various domains, particularly in medical applications. The field is moving towards integrating multimodal data, such as combining text and visual information, to enhance diagnostic accuracy and medical reasoning. This integration is being explored across different medical specialties, including gastroenterology, radiology, and plant disease recognition, among others.

One of the key trends is the evaluation and optimization of these models for specific medical tasks. Researchers are focusing on improving the performance of VLMs and LLMs by fine-tuning them on specialized datasets and employing advanced prompt engineering techniques. This approach aims to leverage the strengths of both proprietary and open-source models, balancing performance with adaptability.

Another notable direction is the exploration of robustness and interpretability in medical applications. As these models are increasingly deployed in real-world clinical settings, ensuring their reliability under diverse conditions and adversarial scenarios is becoming crucial. Techniques such as randomized smoothing and prompt learning are being developed to certify the robustness of these models, addressing concerns about their safety and reliability.

The field is also witnessing a shift towards multi-task learning, where models are designed to handle multiple tasks simultaneously, such as medical report generation, visual grounding, and visual question answering. This multi-task approach not only enhances the versatility of the models but also improves their clinical accuracy by leveraging the synergies between different tasks.

Noteworthy Developments

  1. Integration of Visual Data in Medical Reasoning: The study on the performance of VLMs in gastroenterology highlights the challenges in integrating visual data with medical reasoning tasks. While LLMs exhibit robust zero-shot performance, the integration of visual data remains a significant challenge for VLMs.

  2. Multimodal Retrieval Systems for Plant Disease Identification: The development of a multimodal plant disease image retrieval system demonstrates the potential of combining image and text data to enhance disease recognition. This system leverages a novel CLIP-based vision-language model to encode both disease descriptions and images into the same latent space, enabling cross-modal retrieval.

  3. Visual Prompt Engineering in Radiology: The exploration of visual prompt engineering to enhance the capabilities of VLMs in radiology shows promise in improving classification metrics for lung nodule malignancy. This approach involves embedding visual markers directly within radiological images to guide the model's attention to critical regions.

  4. Multi-task Learning in Chest X-ray Interpretation: The introduction of M4CXR, a multi-modal LLM designed for chest X-ray interpretation, underscores the benefits of multi-task learning in medical applications. M4CXR supports multiple tasks, including medical report generation, visual grounding, and visual question answering, while maintaining high clinical accuracy.

  5. Certifying Robustness via Prompt Learning: The proposed PromptSmooth framework addresses the robustness of medical vision-language models against adversarial attacks. By leveraging prompt learning, PromptSmooth achieves a balance between accuracy and robustness, minimizing computational overhead and handling multiple noise levels efficiently.

These developments collectively advance the field by enhancing the integration of multimodal data, improving model robustness, and expanding the capabilities of VLMs and LLMs in medical applications.

Sources

Vision-Language and Large Language Model Performance in Gastroenterology: GPT, Claude, Llama, Phi, Mistral, Gemma, and Quantized Models

Snap and Diagnose: An Advanced Multimodal Retrieval System for Identifying Plant Diseases in the Wild

Can Visual Language Models Replace OCR-Based Visual Question Answering Pipelines in Production? A Case Study in Retail

Visual Prompt Engineering for Medical Vision Language Models in Radiology

VLM4Bio: A Benchmark Dataset to Evaluate Pretrained Vision-Language Models for Trait Discovery from Biological Images

M4CXR: Exploring Multi-task Potentials of Multi-modal Large Language Models for Chest X-ray Interpretation

PromptSmooth: Certifying Robustness of Medical Vision-Language Models via Prompt Learning

How Does Diverse Interpretability of Textual Prompts Impact Medical Vision-Language Zero-Shot Tasks?

Aligning Medical Images with General Knowledge from Large Language Models